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French Guiana (French: Guyane française, officially Guyane) is an overseas region of France, consisting of a single overseas department located on the northern coast of South America. It has borders with two nations, Brazil and Suriname. Like the other DOMs, French Guiana is also an overseas region of France, one of the 100 regions of France. Its currency is the euro. Almost half the population lives in the suburbs surrounding the region's main city, Cayenne.

The addition of the adjective "French" comes from colonial times when three such colonies existed: British Guiana (now Guyana), Dutch Guiana (now Suriname) and French Guiana. The three are still often collectively referred to as the Guianas.